An idea I saw on another forum: using the collectible minifigs in a way similar to Magic the Gathering drafts.
Every person brings along the same number of unopened minifig bags (or the host supplies them all). Then you open as many bags as there are players. One person picks one of the minifigs, then you open another bag, the next person picks a fig, you open another bag, and so on. When all minifigs are picked, you battle with them.
What do you think?
Remus: Harry... I'm a werewolf.
Harry: Are you fucking serious?
Remus: Well yes, but I don't see how that applies here.